It would be great if the user could input custom expressions within the x or y axis range boxes (either min or max or both). That would allow custom axis configuration with either logic (zoom to not show outliers, etc.) or with document properties from user input. Some of this could probably be done with show/hide functionality, but to me it is not as intuitive even for advanced users, and especially for novice users.
I have had need to use this functionality in the past and I had tried IronPython, but things were buggy because i was running R scripts and IronPython simultaneously and I think I had synchronization issues.